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BPC-157 has been investigated for vascular and angiogenic signalling through VEGFR2 receptor activation and the downstream Akt-eNOS branch, alongside gastric-protection and growth-hormone-receptor-upregulation findings (PMID 27847966, PMID 21030672, PMID 34267654)

Hypothesis: Thanks to a stronger weight loss, CagriSema should lead to a superior reduction of MACE compared to Semaglutide in SELECT (where Semaglutide reduced MACE by 20 %)

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