Available from: MacFarquhar JK, Broussard DL, Melstrom P, Hutchinson R, Wolkin A, Martin C et al (2010) Acute selenium toxicity associated with a dietary supplement
In contrast to their expectations, the results have shown that daily supplementation with vitamin C and vitamin A for 4 weeks not only failed to improve the insulin responsiveness but also decreased the expression of ROS-sensitive transcriptional regulators, molecular mediators of ROS defense (SOD 1 and 2, glutathione peroxidase) [90]
NAC supplementation has been shown to improve clinical pregnancy outcomes in women with PCOS undergoing ovulation induction (OI), likely due to its insulin-sensitizing, antioxidant properties, and protective effects on mitochondrial function, as demonstrated in previous studies
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