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There is no robust body of randomized controlled trial data demonstrating that lipotropic injections cause clinically significant fat loss beyond what the accompanying calorie restriction, activity changes, and clinical monitoring would have produced anyway

Our team can't stress this enough: combining powerful bioactive compounds without a full understanding of their interactions is a formidable risk

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Supporting this hypothesis, increases in glutamatergic compounds have been observed following ketamine administration in the medial prefrontal cortex (mPFC) in studies with rodents 5,6,7