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Immunofluorescence showed that prominin 2 co-localized with markers of multivesicular bodies (MVBs) within 30 min after GPX4 inhibition, most evident in the perinuclear region

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In addition, approximately 1 in 3 participants (31.6%) who received cagrilintide achieved a weight loss 15%, compared to approximately 1 in 20 participants (4.7%) who received placebo