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Current evidence suggests GHK-Cu may provide moderate adjunctive benefits in pigmentation disorder management when combined with established treatments including hydroquinone, kojic acid, or laser therapies, rather than serving as a primary depigmenting agent

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These include (1) tetrahydrobiopterin (BH 4 ), synthesized by the GTP cyclohydrolase 1 (GCH1)6-pyruvoyl-tetrahydropterin synthase (PTS)sepiapterin reductase (SPR) metabolic pathway and regenerated by dihydrofolate reductase (DHFR) 11

Anti-Inflammatory & Antioxidant Effects GHK-Cu fights oxidative stress and chronic inflammation, which are the two major culprits behind aging and disease