While it may seem like the evidence shows that alcohol has significantly more risks than marijuana, the lack of long-term studies on the impact of weed can contribute to this gap
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Cigarette smoke or cigarette smoke extract (CSE), which is used in cell culture experiments, promotes several pathophysiological processes associated with AMD in RPE and surrounding tissues, including oxidative stress, inflammation, cell senescence, and neovascularization resulting in a significantly increased risk to develop AMD [4, 6, 9, 28]