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The normal range for B12 in the US is 200 to 800 pg (picograms)/milliliter of blood

Higher-Caution Situations Extra medical supervision is important if you: have a history of reactions to injectable vitamins/cobalamins have significant kidney or liver disease are pregnant or breastfeeding are offered a compounded MIC B12 product without clear labeling of ingredients, concentrations, and compounding source The FDAs overview of compounding helps explain why quality can vary (see Compounding and the FDA: Questions and Answers )

A lot depends on your current B12 levels and the results you're aiming for

Because gastric absorption rates are unpredictable compared to vitamin B12 injections, according to Foxx, most oral vitamin B12 supplements provide much more than the recommended amount to account for the discrepancy between the dose you take and benefit from (1)