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Regular follow-up should include assessment of weight loss trajectory, tolerability, medication adherence, and renal function if significant GI symptoms occur

Fermentation in the gut yields SCFAs, which lower intestinal pH, inhibit harmful bacteria, and enhance intestinal barrier function and immunomodulation (Lin et al., 2021

A conjugation of AITC to glutathione in planta might be non-enzymatic or catalysed by GSTs, as indicated by the AITC-induced upregulation of several GST-encoding genes 17,40,41 and similar to what was recently shown for indol-3-ylmethyl-ITC 35

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