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5% due to alternative cytochrome P450 depending glutathione (GSH) conjugation pathway At high doses : Glucuronidation and sulfation pathways become saturated Cytochrome P450 dependent pathway becomes now more important.With depletion of hepatic glutathione, hepatotoxic, reactive, electrophilic metabolites are formed

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Preservative-Free Formula: Made in the USA with all-natural ingredients and no preservatives, offering a gentle and wholesome option for sensitive or aging pets

Discomfort: Over-the-counter pain relievers like acetaminophen (Tylenol) can help if needed