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Despite representing different neurological diseases and being induced by diverse triggers, the mouse model of each disease displays similar alterations in mRNA expression in the BBB at subacute time points with the worst function [13]
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NTHi invasion of host epithelial cells may not only provide a means of evading host immune pressures, but also provide an alternative reservoir for nutrient acquisition when bacteria are exposed to nutrient-limiting conditions ( sapA mutants deficient in haem-iron uptake demonstrated a tendency towards a more persistent phenotype, favouring intracellular survival and a dampened cytokine response compared to the parent strain (Raffel et al., 2013)
Through a combination of these molecular and stimulation techniques, Pohodich et al
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