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Common injection sites include the thigh, shoulder, and buttocks

When joint discomfort occurs after starting B12, it is typically coincidental or related to other factors such as excipients in formulations, injection-site effects, pre-existing musculoskeletal conditions, or rare hypersensitivity reactions rather than a direct effect of the vitamin itself

What they did: Obese mice received AOD-9604 orally (via gavage) for 14 days at various doses (50, 250, 500 g/kg)

Injection-Related Complications : Use of injectable forms can lead to infection, irritation, improper dosing, or tissue damage if not handled under medical-grade conditions