Heart rate increased from baseline across all treatment groups, an effect consistent with prior trials of semaglutide
Research has shown that MT1G plays a crucial role as a tumor suppressor in pancreatic cancer stem cells
Here, most effects were found in pathways citric acid cycle and respiratory electron transport (q-value: 3.5 * 10 10 , 63 DEGs out of 171 genes, 76.2% downregulated), glucose metabolism (q-value: 9.9 * 10 9 , 36 DEGs out of 77 genes, 80.5% downregulated) and metabolism of lipids and lipoproteins (q-value: 2.9 * 10 6 , 165 DEGs out of 728 genes, 55.2% downregulated)
doi: 10.3389/fnmol.2021.742294 Received 16 July 2021 Accepted 23 August 2021 Published 09 September 2021 Volume 14 - 2021 Edited by Jun Hirayama, Komatsu University, Japan Reviewed by Sooyoung Chung, Ewha Womans University, South Korea