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During deep sleep: Growth hormone secretion peaks, driving tissue repair and muscle recovery The brains glymphatic system clears metabolic waste products, including proteins associated with neurodegeneration Cortisol levels reach their daily minimum, allowing the adrenal system to reset Immune function regenerates Cellular repair mechanisms run at maximum efficiency Most adults spend less time in deep sleep than optimal, and this deficit increases with age, stress, alcohol consumption, and certain medications

International archives of allergy and immunology , 149 Suppl 1 , 102-7 Ghiaur, Gabriel

Genetic depletion of LIAS and DLAT , like FDX1 deletion, confers resistance to cuproptosis (Tsvetkov et al., 2022)

& Coe, F