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Contraindicaciones Relativas Enfermedad del higado: Los pacientes con insuficiencia heptica grave deben utilizar la inyeccin de Eptona con precaucin, dado el riesgo de hepatotoxicidad

4.6 Liver fibrosis Liver fibrosis is a pathological alternation present in the course of most chronic liver diseases (Mederacke et al., 2015)

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Since venetoclax and AZD-5991 rapidly induce apoptosis in CLL cells, these compounds were added in the last 24 hours of incubation to minimize single-drug cytotoxicity