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98 (12): 46554663, Maryam Yavari et al

10.2174/1381612824666180608101119 71 SikiricP.SeiwerthS.BrcicL.BlagaicA

Moreover, according to Sarafian et al, prior studies have shown that chronic marijuana exposure causes a continual decline in GSH antioxidant systems and result in necrotic apoptosis [313], providing further evidence of THCs cytotoxic effects

3.2 Molecular mechanisms of mitophagy Mitophagy, which may be described as a process of eating itself, is the selective isolation of excess or damaged mitochondria by autophagosomes, which are then degraded by lysosomes (Pickles et al., 2018)