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doi: 10.3390/ijms19092605 144 CarreauAKiedaCGrillonC

Paraffin sections were stained using the AB-PAS method and then examined and quantified for goblet cells under a microscope ( TABLE 2 Scoring criteria for histological changes

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After the effector molecules of JAK (such as cytokines, IFN, colony-stimulating factors, and growth factors) bind to type I and type II receptors (these receptors consist of various subunits, each of which is associated with a JAK molecule), JAK is activated and provides a docking site for STAT molecule by transferring phosphate to the tyrosine residues of receptor subunits through autophosphorylation, followed by STATs phosphorylation-mediated signal transduction of the nucleus (223)