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For adaptive immunity, it restores the balance of T-cell subsets, promoting regulatory Treg differentiation, inhibiting pathogenic Th17 and autoreactive CD8 + T cell activation, and regulating Tfh cell function

May Reduce Inflammation Preliminary studies suggest that NNMT inhibition may lower systemic inflammation markers , helping reduce the oxidative stress burden that accelerates aging and disease progression

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There may be a number of sources of this oxidative stress, including mitochondrial superoxide production, ischemia-reperfusion mechanisms and auto-oxidation of catecholamines