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If a patient cant tolerate allopurinol and meets the criteria (see above) for probenecid, that can be tried

Analysis on patents of health care products with substances of medicine food homology in China

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Although H 2 S production was not directly measured, increased levels of SAMan allosteric CBS -activatorin arterial cord blood in severe IPTB cases, regardless of treatment (and in venous blood, especially following NAC-treatment) suggest a potential role of SAM in counterregulatory responses