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Senescent cells exhibit higher expression and release of SASP factors [7, 8, 15]

In a study of smokers with asthma, those who quit smoking for six weeks showed a significant increase in FEV1 (Forced Expiratory Volume in one second) and a reduction in sputum neutrophils, highlighting the benefits of quitting even in the short term

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The mTOR pathway can be activated by high levels of nutrients and energy, such as a high ATP/ADP ratio, growth factors and oxygen, which promote anabolism and inhibit catabolism [72, 73]