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Nevertheless, researchers, lacking substantial evidence supporting the involvement of peripheral pain tissue anomalies and nociceptive processes in fibromyalgia, tend to emphasize the study of central sensitization [12,47]

Mitochondrial dysfunction itself can be categorized into two types: the first type represents a mutation of a gene which is associated with the ATP-generating pathway, while the second one is related to various abnormalities such as genetic, biochemic or metabolic, that may weaken the ability of the mitochondria to produce ATP (Haas et al., 2007)

doi: 10.3390/microorganisms9071486 410 SzntMDzsaAAntalDSzabKKemnyLBaiP

In some embodiments, the formulation or composition has a viscosity between about 10 cP to about 500 cP