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The downregulation of myeloid zinc finger 1 (MZF1) expression, which activates the Nrf2/GPX4 pathway and inhibits rankl-induced ferroptosis in osteoclasts during early cell differentiation, may be a key mechanism underlying ovarian removal (OVX) mice models of postmenopausal osteoporosis (37)

For testing, animals were anesthetized with ketamine (80 mg/kg) and xylazine (10 mg/kg) via i.p

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I am still finding the use of the medications and what they are actually do difficult to get my head around - if reducing the dose of Carbimazole resolves HypO, why did the Endo prescribe going back onto 100 micro grams Levothyroxine instead of reducing the dose of 40 mg Carbimazole