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Conventional high- definition upper endoscopy is the gold standard for screening and diagnosis of BE

Considering that follicles close to the OE lesion tissues exhibit higher total iron levels and lower oocyte retrieval rates than follicles in healthy ovaries [28], iron overload in the OE may impair oocyte maturation and function by affecting granulosa cells close to the lesion and further mediate the release of abnormal exosomes of granulosa cells

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