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Published preclinical work used a wide range of oral doses

HDACi inevitably disrupt both gene expression and signaling networks, leading to multi-target, non-specific biological effects

Clin Exp Allergy 43(1):3649 Stenius-Aarniala B, Poussa T, Kvarnstrom J, Gronlund EL, Ylikahri M, Mustajoki P (2000) Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study

work, Ipamorelin released GH with potency comparable to the older peptide GHRP-6 but, unlike GHRP-6 and GHRP-2, did not meaningfully elevate adrenocorticotropic hormone (ACTH), cortisol, or prolactin even at doses well above the GH-releasing threshold