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When the cells of your body are exposed to chemical signals for a prolonged period of time, they tend to lose their ability to respond to the stimulus with its original intensity

Note that some y-axis scales are discontinuous to better illustrate variants with very small P -values (e.g., the Drinks per Week y-axis is cut at 30 with a maximum value of 307.7, denoting a P -value of 1.9 10 308 )

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Activation of innate immunity in primary human cells using a plant virus derived nanoparticle TLR7/8 agonist