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References: Katzung BG (2021): Introduction to Autonomic Pharmacology (Chapter 6)

The addition of oxygen during HMP is aimed at reducing ischaemiareperfusion injury, but has shown mixed results in kidney transplantation, often depending on the duration of perfusion, although some studies found that the addition of oxygen improved outcomes in higher-risk donors

Misunderstanding the results can lead to unnecessary anxiety, inappropriate interventions, or a false sense of security

DOX treatment significantly increased the apoptotic DNA fragmentation index in skeletal muscle by approximately 100% compared to controls, confirming its pro-apoptotic toxicity