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Sustained remission is defined as meeting no criteria for SUD (except craving) for at least 12 months, according to a release by the American Psychiatric Association titled Highlights of Changes from DSM-IV-TR to DSM-5 . Elimination of physiological subtype and polysubstance dependence: The DSM-5 eliminates the DSM-4 diagnoses of polysubstance abuse and the physiological subtype specifier for dependence