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Although preclinical studies have yielded encouraging results, clinical validation through Phase I/II trials is essential to confirm their safety and efficacy in humans

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Keywords: : glutathione, 25-hydroxyvitamin D, vitamin D binding protein, vitamin D receptor, inflammation, insulin resistance Introduction Changes in modern lifestyles that limit physical and outdoor activity and increased consumption of high-energy diets have led to a high incidence of obesity and diabetes and widespread inadequacy/deficiency of 25-hydroxyvitamin D [25(OH)VD] in populations worldwide

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