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Oxidative stress and epilepsy

A and Tau can also trigger upregulation of the type-1 interferon response genes (Sanford and McEwan, 2022) (similar to ApoE as discussed earlier) that would suggest antiviral synergy

The FDA's 2023 PCAC briefing document cited insufficient clinical evidence to support therapeutic compounding approval

(6) Complex I: Complex I (NADH:ubiquinone oxidoreductase) is a large multiprotein complex located in the mitochondrial inner membrane that accepts electrons from NADH and transfers them to ubiquinone (CoQ 10 ) via FMN and a series of ironsulfur (FeS) clusters, reducing it to ubiquinol (CoQ 10 H 2 ) 68,69