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The intent is synergy: one peptide supports repair signaling, another supports tissue organization, and another supports structural rebuilding

Baseline Assessment Before Starting ALA Before adding ALA at any dose to a rosuvastatin regimen, obtain or review: Fasting plasma glucose and HbA1c (to characterize baseline glycemic status) TSH (to rule out pre-existing hypothyroidism that could worsen) Creatine kinase (to document a baseline in case myalgia develops and thyroid effects are later implicated) Ongoing Monitoring by Dose At ALA doses of 300 mg/day or below in normoglycemic patients, no additional monitoring beyond routine statin follow-up is required

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Adherent PBMCs were lysed with cold sterile nanopure water, collected in microcentrifuge tubes, and stored at 80 C for the subsequent assessment of relevant biomarkers