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For example, (+)-medioresinol, isolated from Sambucus williamsii , promotes the accumulation of reactive oxygen species (ROS) and induces cell cycle arrest, ultimately triggering apoptosis in fungal cells (Hwang et al., 2012)

Altered DNA methylation patterns, specifically levels of methylation (5 mC) and hydroxymethylation (5 hmC), are commonly associated with type 2 diabetes (T2D) and general oxidative stress [63]

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