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In addition, to facilitate regulatory acceptance, applicants should clearly describe their NAM, including the context in which the NAM will be used (e.g., for screening/prioritization or quantitative risk assessment), the relevance of the model system to human biology and mechanisms of toxicity, and how the NAM informs the toxicological issue/gap

Shipping or purchasing unstamped tobacco off-reserve is illegal for non-Indigenous individuals

Note: Make sure that all of the plastic guide pins and metal spring clips are aligned properly to their slots before pressing the trim pieces back in to place

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