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For single-agent studies, the Ipamorelin Peptide is widely utilized in controlled laboratory settings

Prevention and treatment Diet Including foods with vitamin B12 and folate (listed above) in the diet is the first step to preventing and treating low levels of these vitamins

Analysis of single-cell RNA sequencing Single-cell RNA sequencing (scRNA-seq) data (HRA000425) were downloaded from Genome Sequence Archive (SRA)-Human databases in China National Center for Bioinformation 16 , converted into FASTQ format using fasterq-dump software (sratoolkit 3.0.2, NCBI, NIH, Bethesda, MD, USA), converted into a matrix data file using Cell Ranger software version 3.0.2 (10xGenomics, Pleasanton, CA, USA), converted into Seurat objects using Seurat 5.0.1 software (Satija lab, Lower Manhattan, New York, NY, USA), and plotted for t -distributed stochastic neighbor embedding ( t -SNE) visualization

Densitometry analysis was performed using ImageJ6.0 software (National Institutes of Health, Bethesda, MD, United States)