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The adolescent cardiovascular systemcharacterized by active vascular remodeling and an immature endotheliumis especially vulnerable to the oxidative stress and inflammation induced by e-cigarette aerosols ( Nicotine and other chemical components of vaporized e-liquids can impair endothelial function, increase arterial stiffness, and elevate blood pressurerecognized early markers of cardiovascular disease ( Given the prognostic value of elevated blood pressure and arterial stiffness as predictors of cardiovascular morbidity and mortality, these findings raise serious concerns about the potential lifelong cardiovascular consequences of vaping initiation during adolescence

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Despite years of aggressive efforts to tackle the leading cause of preventable disease and death in the United States, he added, tobacco use largely cigarette smoking still kills more than 480,000 Americans every single year. The measure will lower nicotine levels to minimally or non-addictive levels, the agency said