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doi:10.18502/ijrm.v17i10.5296

611 Additionally, isoliquiritigenin, a common herb used in traditional Chinese medicine, inhibits the expression of PGC-1 at protein level and enhances ROS accumulation in gastric cancer cells, but PGC-1 overexpression partly reverses the inhibition of ISL on cell viability

In addition, we address sex and gender differences in this bidirectional relationship

Recent developments in automated sampling of blood (159) and tissue interstitial fluid via microdialysis (160) have also uncovered the ultradian rhythms in plasma ACTH which correlate well with plasma and tissue steroid (cortisol and cortisone) concentrations, indicating that the ultradian rhythms in blood ACTH and cortisol/cortisone translate well to tissue exposure to these steroids