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However, if split dosing improves your adherence and reduces side effects, the practical benefit may outweigh theoretical pharmacokinetic concerns

Lower dose for days 1-15, then doubled dose for days 16-30

Normal and expected reactions include a brief stinging or burning sensation during or immediately after injection, mild redness or warmth at the injection site lasting a few minutes, and small temporary lumps that resolve within 30 to 60 minutes as the solution disperses through subcutaneous tissue

A physician, however, will be familiar with the potential dangers and can decide whether to prescribe B12 shots based on his or her knowledge of the patients medical history