Critical Perspective and Limitations Despite extensive evidence supporting the potential benefits of antioxidant supplementation in dogs, several important limitations must be acknowledged
This may include instances where: You need a stronger product to achieve your goals (e.g., deep hyperpigmentation, severe acne, etc.) You already use another product containing copper (this could be unsafe) An essential part of your skin care routine is a harsh active, vitamin C, strong exfoliant, or salicylic acid many of which are common ingredients in acne treatments and anti-aging products (copper peptides shouldnt be mixed with them) Using copper peptides may be unsafe (i.e., you have Wilsons disease, a peptide allergy, or active/suspected cancer) Youve tried a copper peptide product in the past and experienced an adverse reaction (e.g., copper uglies or troublesome side effects) If youd like some alternatives to copper peptides, we go over a few in the Alternatives to copper peptide serums section later in this guide
Transport There are few measurements of overall transport rates of the metabolites between the compartments of the model
However, the clinical efficacy of these treatments is often hampered by factors such as rapid drug clearance and inadequate drug delivery to the site of arterial injury 4,5,6
