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Nevertheless, despite the administration of a higher dose of LA for a prolonged period (1200 mg/day for 12 weeks), the intensity of liver steatosis in obese patients with MASLD was not significantly enhanced

As lipid peroxidation occurs, endogenous aldehydes and their derivates, such as glyoxal, methylglyoxal (MG), malondialdehyde (MDA) or 4-hydroxy-2-nonenal (4-HNE), are formed with high reactivity and toxicity for cell components

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