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10.1111/ajd.12290 200 RojiM.SebastianM.LuccaJ

In atherosclerosis, macrophages take up OxLDL to form foam cells and orchestrate inflammatory and reparative responses within vascular lesions, thereby playing a pivotal role in plaque formation and progression (28,34,36)

Additionally, the gut microbiota regulates the accumulation of Th17 cells in the lungs by affecting the expression of RegIII (an IL-22-induced antibacterial protein specific to Gram-positive bacteria) and IL-22, thus impacting the immune response during fungal infection (63)

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