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Unlike beta-1 receptors in cardiac tissue or beta-2 receptors in smooth muscle, beta-3 receptors are predominantly expressed in adipose tissue and bladder, with limited cardiovascular effects

Microscopy From rats, at end of the experiment, the brain, liver, kidney, stomach, duodenum, jejunum, colon, rectum, lungs, and heart were fixed in 10% neutral buffered formalin (pH 7.4) at room temperature for 24 h

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