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CRISPR-Cas9-mediated knockout of GCN2 reveals a critical role in sensing amino acid deprivation in bovine mammary epithelial cells

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Results ACTL6A is overexpressed in GC and promotes GC progress First, analysis of mRNA expression data obtained from the GC datasets GSE13911, GSE27342, GSE13861 in the Gene Expression Omnibus (GEO) demonstrated that the ACTL6A expression level was higher in cancer tissues than in normal tissues (Fig