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doi: 10.1196/annals.1297.059
NO-releasing agents, such as JS-K ( O 2 -(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate) 123 and PABA/NO ( O 2 -[2,4-dinitro-5-( N -methyl- N -4 carboxyphenylamino)phenyl] 1- N , N -dimethylamino)diazen-1-ium-1,2-diolate) 124 , are able to induce differentiation and cell death in a variety of cancer cells through GSH consumption, DNA synthesis inhibition and inhibition of enzymes involved in the defense against cell damage
doi: 10.1128/CMR.17.2.255-267.2004 74 KolterR.GreenbergE
On the other hand, antioxidants can protect the cells from incident radiation through specialized pigments and control the levels of reactive species which otherwise might cause a cascade of reactions and lead to the generation of pathological oxidants [63]
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