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Table 6: Treatment of folate deficiency (adapted from Means 2021) 27 TOP Ongoing Care Ongoing Management Vitamin B 12 Duration of therapy Once a diagnosis of B 12 deficiency due to poor absorption of B 12 has been made, therapy should be maintained lifelong

Gastrointestinal Research Much of the initial work focused on the digestive tract

Pregnant and breastfeeding women should avoid the peptide due to unknown effects on fetal and infant development

Of the 14 cases reviewed, all were taking doses over 1000 mg per day Vitamin B6 deficiency occurred more rapidly from onset of treatment in those taking over 1500 mg per day