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Studies have also shown that treatment with ALA can decrease acute kidney injury by lowering serum blood urea nitrogen, creatinine levels, tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1), thereby decreasing endothelin-1 vasoconstriction, neutrophil diffusion, and inflammation in the kidneys

Population pharmacokinetics of sarilumab in patients with rheumatoid arthritis

Side effects are typically mild and include injection site reactions or transient water retention

To what extent systemic infusion of anti-CD20 monoclonal antibodies may deplete B cells or CD20-expressing T cells (Sabatino et al., 2019