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10.1186/s13045-022-01297-1 307 XiongH.WangC.WangZ.JiangZ.ZhouJ.YaoJ

Alpelisib plus fulvestrant in PIK3CA-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study

Watanabe, Fumiko, et al

Zinc typically needs to be taken three times per day, but the oral chelators can be taken twice daily, an easier regimen which tends to enhance adherence