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Inhibition of gasdermin D-mediated pyroptosis attenuates the severity of seizures and astroglial damage in kainic acid-induced epileptic mice

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Furthermore, treating lymphocytes with CDT leads to perturbations in PI3K signaling, including phosphatidylinositol-3,4,5-triphosphate (PIP3) depletion, and decreases both Akt and GSK3 phosphorylation