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Glutathione S-transferases (GSTs) catalyze the conjugation of GSH to a broad range of electrophilic compounds, including endogenous signaling molecules, reactive aldehydes such as 4-hydroxynonenal (4-HNE), and heavy metals 13,14

Knockdown or knockout of PDGFRA in gastrointestinal (GI) and glioblastoma (GBM) cancer cells suppressed tumour proliferation [90,91,92]

For example, studies have demonstrated that certain components of Chinese medicine alleviate depressive symptoms by regulating intestinal microbiota metabolites, which may also serve as targets for new drug development [607]

Design and modification of anticancer peptides