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Journal of Oral Rehabilitation 47(2):150157 Chojnacki C et al (2022) Altered tryptophan metabolism in patients with recurrent functional abdominal pain

This epithelial damage and subsequent unrestricted paracellular permeability has been observed in graft vs host disease and gastrointestinal conditions such as Crohn's disease and ulcerative colitis [39], and may play a role after acute cardiovascular events, such as after a stroke, where damage to intestinal epithelial cells is severe [40]