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N Biotechnol 30:219226

In addition, extracellular lactate stabilizes HIF-2, and HIF-2 then transactivates MYC, increasing the levels of glutamine transporters and GLS1, in turn resulting in increased glutamine catabolism 72

Theyre popular in biohacking, bodybuilding, and regenerative medicine communities but not FDA-approved for human use sold as research chemicals. Evidence is mostly from animal studies, rodent models, and anecdotal reports