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Further, given the observations reported here, the comparison of test substance exposures to their respective vehicle treatment may not be sufficient to normalize data for comparison or extrapolation to in vivo human exposure outcomes

For example, if you swap out filters with the mask on, tear gas could enter the mask through the hole and reach your eyes and skin

Further research and system-focused responses are needed to understand and address such complexities, such as optimizing the NBPT to incorporate ethnicity, rurality, and socioeconomic status in its criteria [7, 16]

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