5 Regulation of adaptive immunity by innate immunity in vitiligo Vitiligo is an autoimmune disease driven by dysregulated adaptive immunity, where autoreactive CD8 + T cells selectively destroy melanocytes, leading to progressive skin depigmentation
The PEMT enzyme also requires SAM as a cofactor
The following data were collected: publication year, country and continent, study setting (e.g., hospital, private practice, academic clinic), sample size, age range, mean age, study design, population characteristics, intervention details, outcomes, and effect measures (e.g., serum B12 levels)
Neither cagrilintide nor retatrutide is currently approved for clinical use in the United Kingdom